Congratulations to Dong and Yiyun! The paper "Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression" has been published by Nature Genetics!


Welcome Fufang QIU to join the lab as a Visiting Student!


Welcome Dr. Yunqing LIU to join the lab as a Postdoc Fellow!


Welcome Dr. Zheng WANG to join the lab as a Postdoc Fellow!


Congratulations to Junyi and Zongchao! The manuscript "MGSA: a Multi-ethnic Germline-Somatic Association database to decipher multi-layered and interconnected genetic mutations in cancer" has been provisionally accepted for publication in Cancer Research.


Congratulations to Zheng ZHAO and Zongchao! The paper "circRNADisease v2.0: an updated resource for high-quality experimentally supported circRNA-disease associations" has been published by Nucleic Acids Research.


Congratulations to Quanhua and Ruichao! The pan-glioma evolution paper has been published by Science Translational Medicine.


Welcome joint program students, Can NI (primary advisor: Prof. Qinglu ZENG) and Mengqi YANG (primary advisor: Prof. Kun SUN), for joining us.


Congratulations to Yiyun CHEN, Zheng ZHAO and other lab members! Our study on Tumor-associated monocyte (TAMo) is now online. The study has revealed a functional myeloid cell in glioblastoma, TAMo, which specifically expresses EREG and AREG, promoting mesenchymal transformation through the FOSL2-EREG/AREG-EGFR axis.


Welcome Minghao WANG, Qi AN and Jooran LEE to join the Wang lab as RPG students.


Congratulations to our newly established SIAT-HKUST Joint Laboratory of Cell Evolution and Digital Health, at HKUST Shenzhen-Hong Kong Collaborative Innovation Research Institute, Futian, Shenzhen. More Photos


Congratulations to Yingxi YANG who wins the HKUST RedBird Academic Excellence Award for Continuing PhD Students in 2022-23.


Congratulations on the great success of our BAM workshop 2023!


Congratulations to Dr Yingxi YANG. She has succesfully passed the PhD exam!


Congratulate to Jooran LEE for being awarded the 2023/24 Asian Future Leaders Scholarship Program (AFLSP)!


Welcome Dr Zheng ZHAO to join the lab as a Postdoc Fellow!


Congratulate Quanhua MU for his promotion to Research Assistant Professor at CBE.


Congratulations to Zhi HUANG and Yuyan RUAN, who won the RedBird PhD Award for new PhD sudents.


Welcome Mengli YAN, Yuyan RUAN and Zhi HUANG, who join the Wang Lab as RPG students.


Welcome Ruichao CHAI and Hui WANG, who join the Wang Lab as postdoc fellow.


Congratulations to Yiyun CHEN, who will join Stanford University for postdoc study.


Congratulations to Yingxi, who has been selected from a highly competitive pool of candidates to receive the HKUST RedBird Academic Excellence Award for Continuing PhD Students in the 2021/22 Academic Year.


Congratulations to Jiabao LI who won the Hong Kong PhD Fellowship Scheme (HKPFS).


Congratulations! Wet lab open at Room 6201M (Zone J)!


Congratulations to Yoonhee, joining the Columbia University, in the city of New York for her postdoc study.


Welcome Mengli YAN, who joins the Wang Lab as a research assistant.


Congratulations to Biaobin JIANG, Quanhua MU, and Fufang QIU! The MetaNet manuscript entitled "Machine learning of genomic features in organotropic metastases stratifies progression risk of primary tumors" has been officially accepted for publication in Nature Communications. Click here for details.


Congratulations! The bAVM paper has been highlighted at the Cover of Volume 129, Issue 9 of Circulation Research on October 15, 2021. https://www.ahajournals.org/toc/res/129/9. Yoonhee Nam has been highlighted in the "Meet the First Authors" section of Circulation Research: https://www.ahajournals.org/doi/10.1161/RES.0000000000000515.


Congratulations to Yoonhee, Biaobin, Qiuxia, Dong, and Yingxi! The comprehensive multi-omics study of brain arteriovenous malformation (bAVM) has been published online as an original article at Circulation Research. It has been a collaborative project with Prof. Yong Cao's team at Beijing Tiantan Hospital.


Congratulations to Jihong TANG who won the Hong Kong PhD Fellowship Scheme (HKPFS)!


Welcome Jihong and Ruochen, who join the Wang Lab as RPG students.


Welcome Junyi, who joins the Wang Lab as a Postdoctoral researcher.


Congratulations to Yingxi, who has recieved the Chan Tak Kei & Wong Kwai Ying Bioengineering Student Research Award! The awards, presented annually, recognize students’ excellence in research during their studies in BIEN graduate program.


Welcome Haixia, who joins the Wang Lab as a Postdoctoral researcher.


Congratulations to Prof. Jiguang WANG. He has been promoted to Associate Professor and appointed as Padma Harilela Associate Professor of Life Science.


Congratulations to Prof. Jiguang WANG, who has recieved the 2020/21 School Research Award from School of Science, HKUST, in appreciation of his excellent performance in research.


Congratulations! Yurong WU, the UROP student in our lab, has been elected to the finalist of the 2021 Mr Armin and Mrs Lillian Kitchell Undergraduate Research Award!


Congratulations to Yingxi, Dong, Yiyun, and Yoonhee! The Cerebral Cavernous Malformation (CCM) study has been officially accepted by American Journal of Human Genetics. In this study, we discovered and elucidate the role of MEKK3-I441M in CCM. The I441M mutation that actives kinase activity in CM endothelium is a fascinating finding that not only reveals etiology of popcorn-like CM but also provides a theoretical foundation for developing non-invasive methods for genotyping, patient diagnosis and potential targeted therapy against vascular malformations. Well done!


Congratulations to the acceptance of "Classifying gastric cancer using FLORA reveals clinically-relevant molecular subtypes and highlights LINC01614 as a biomarker for patient prognosis" in Oncogene! The FLORA pipeline (https://github.com/WangLabHKUST/FLORA) developed by Yiyun CHEN, Hongyu SHI, Shengshuo HUANG and Prof. Jiguang WANG was applied to comprehensively profile the long non-coding RNAs and revealed lncRNA-based subtypes in gastric cancer which robustly predict patient survival. In collaboration with Prof. Jun Yu's lab at Chinese University of Hong Kong, the LINC01614 was verified as an oncogenic lncRNA that promotes gastric cancer proliferation and metastasis, and is a potential biomarker in gastric cancer.


Congratulations to Quanhua MU, Zhaoshi BAO and Prof. Jiguang WANG, whose recent publication at Nature Communications has been selected as one of the top 10 Chinese glioma research advances by the Chinese glioma collaborative research group!


Congratulations! Dr. Zhaoshi BAO has been selected as a recipient of the Beijing Distinguish Young Scientists Fund.

Welcome Dr. Yumeng GUO to join the Wang Geonomics Lab as a Postdocal researcher.

Welcome the new students: Zongchao MO (LIFS PhD program), Zhihan ZHU (BIEN Mphil program) and Jiabao LI (LIFS Mphil program)!


Congratulations to Ming Hong Lui who has won the Joseph Needham Merit Scholarship.

Prof. Jiguang WANG has been appointed to serve on the Editorial Board of GPB (Genomics, Proteomics & Bioinformatics), an international peer-reviewed journal published by Elsevier with an Impact Factor 6.597.


Prof. Jiguang WANG has been awarded the Asian Universities Alliance (AUA) Scholars Award.

Congratulations to Ming Hong (James) Lui who won the Hong Kong PhD Fellowship Scheme (HKPFS)!


Congratulations to Yiyun CHEN who won the 2019/20 School of Science Postgraduate Research Excellence Award.


Prof. WANG has been appointed as an Academic Editor of The Innovation between March 2020 and March 2023. The Innovation is a new transdisciplinary journal via the co-operation between Cell Press and YIPA (Youth Innovation Promotion Association, CAS) members.


Prof. Jiguang WANG has joined the Editorial Board of Journal of Molecular Cell Biology (JMCB), an Open Access journal with 5 year Impact Factor 5.856.


Welcome Wei SHEN, who joins the Wang Lab as a Postdoctoral researcher.

Welcome Yingxi YANG, who joins the Wang Lab as a PhD Student.

Congratulations to Paula Weidemüller, who has got accepted to the EMBL-EBI PhD Programme together with the University of Cambridge!

Welcome Dong SONG to join Wang Lab! Congratulations to Dong SONG, who has won the Hong Kong PhD Fellowship Scheme (HKPFS)

Congratulations to Yiyun CHEN for receiving the George K Lee Foundation Scholarships of 2018/19.

Welcome Dr. Zhaoshi BAO, who joins the Wang Lab as a Postdoctoral researcher.

Welcome Wing San Luk, Harry Park and Elfarouk Harb, who join the Undergraduate Research Opportunities Program (UROP) in Wang Lab.

Congratulations! Prof. Jiguang WANG, LIFS/CBE, and his collaborators from Beijing Tiantan Hospital have been recognized as the architects of one of China’s top 10 research advances in life sciences in 2018 by The Chinese Union of Life Science Societies.

HKUST-BJNI-SMC Joint Workshop on Imagenetics was held in Shenzhen, China, Nov 30 - Dec 2, 2018.

New Technologies and Translational Applications in Genomics was held in HKUST, Hong Kong, Nov 7 - Dec 9, 2018.

Imagenetics meeting was held in HKUST, Hong Kong, Oct 22, 2018.

Congratulations to Quanhua, Yiyun, Biaobin and Yoonhee who have uncovered the mutational landscape of secondary glioblastoma (sGBM) in East Asian cohort, through a fruitful collaboration mainly with Dr. Tao Jiang's team from Beijing Neurosurgical Institute and Beijing Tiantan Hospital. This systematic study reveals genomic differences among low-grade glioma, primary glioblastoma and sGBM. Strikingly, we discovered that genomic mutations that lead to METex14 are highly enriched in sGBM cases, and the presence of METex14 transcripts is an important biomarker that predicts significantly worse patient survival. More importantly, MET protein is an actionable drug target, which has been verified in a MET-targeted Phase I clinical trial led by our collaborator at Beijing Tiantan Hospital. Out of the six sGBM patients who completed the trial, two achieved partial response, two achieved stable disease, and two have progressed disease. This encouraging result highlights the great potential of precision cancer medicine in treating previous incurable cancers by tailoring particular therapies according to personalised genomic information.

Welcome Xiangcheng SHI, who joins the Wang Lab as MSc Student.

Welcome Fufang QIU, who joins the Wang Lab as MSc Student.

Welcome Paula Weidemüller, who joins the Wang Lab as Intern Student.

Congratulations! Quanhua received SENG Top RPG Award in 2017/18.

Congratulations! Yiyun has been chosen for the Overseas Research Award of the university in 2017/18.

Congratulations! Biaobin received travel award in The 1st AsiaEvo Conference.

Welcome Mingrui JIANG, who joins the Wang Lab as Research Assistant.

Welcome Shengshuo HUANG, who joins the Wang Lab as PhD student.

The kick-off meeting of The Asian Glioma Genome Atlas (AGGA) has been successfully held in Beijing. Our team is one of the three founding members. AGGA is a precision neuro-oncology collaboration between China and Korea, aiming to create a comprehensive framework to study RNA sequencing, DNA sequencing, imaging, clinical and drug-screening data from more than 1,500 patients.

Congratulations! In a collaborative project with Dr. Kitai Kim at MSKCC, Quanhua MU has been listed as a co-author on the paper titled "RNA exosome complex-Mediated control of redox status in Pluripotent Stem Cells".

Welcome Ming Hong Lui (James), who join the Wang Lab as an undergraguate research student.

Welcome Hanli HUANG, who join the Wang Lab as Research Assistant.

Welcome Nasir Mahmood Abbasi, who join the Wang Lab as Research Assistant.

Jiguang WANG was invited as a speaker in the China Society of Biotechnology Young Scientists Forum II, Guangzhou.

Jiguang WANG was invited as a Keynote Speaker in the 1st annual meeting of Society for Neuro-Oncology of China at China National Convention Center, Beijing.

Congratulations to Biaobin, who has just been appointed as an Institute for Advanced Study (IAS) Postdoctoral Fellow.

Welcome Hongyu SHI and Tianci WANG, who join the lab as UROP students!

Welcome Yiyun CHEN, Yoonhee Nam, and Quanhua MU, who join the lab as PhD students.

Jiguang WANG was invited as a Keynote Speaker in the 8th Institute for Refractory Cancer Research (IRCR) International Symposium held on January 13, 2017 at Samsung Medical Center (SMC) in Seoul, Korea.

Our noncoding RNA work was highlighted in Columbia Newsroom: "Map Quest: New Techniques Reveal How the Immune System Stays Nimble".
Jiguang WANG was invited as a speaker in a Nature conference: "The Genomics of Common Diseases 2016".
Jiguang WANG was named one of the winners in the Best Poster Competition: "Young Investigators Celebrated at Department of Systems Biology Retreat".
The GBM paper is highlighted by the TCGA website at NIH: "Longitudinal Study Charts Brain Tumor Evolution".
Home page of the Wang Lab launches at HKUST.
The findings on GBM evolution are highlighted by Cancer Discovery: "Brain Tumors Under Therapy Undergo Highly Branched Clonal Evolution".
Our GBM research is reported by the Department of Systems Biology at Columbia: "Study of Glioblastoma Tumor Evolution Reveals Strategies Against Advanced Disease".