We have discovered a novel type of noncoding RNA, xTSS RNA, which is expressed at antisense TSS regions of genes that accumulate AID-mediated somatic mutations
A 3D computational model to simulate the multifocal glioblastoma showed the spatiotemporal model of the tumour formation. The tumour cells were coloured by tumour lesions and mutational profiles.
05-12-2023 Congratulations to Dong and Yiyun! The paper "Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression" has been published by Nature Genetics!
13-11-2023 Welcome Fufang QIU to join the lab as a Visiting Student!
13-11-2023 Welcome Dr. Yunqing LIU to join the lab as a Postdoc Fellow!
29-10-2023 Welcome Dr. Zheng WANG to join the lab as a Postdoc Fellow!
29-10-2023 Congratulations to Junyi and Zongchao! The manuscript "MGSA: a Multi-ethnic Germline-Somatic Association database to decipher multi-layered and interconnected genetic mutations in cancer" has been provisionally accepted for publication in Cancer Research.
29-10-2023 Congratulations to Zheng ZHAO and Zongchao! The paper "circRNADisease v2.0: an updated resource for high-quality experimentally supported circRNA-disease associations" has been published by Nucleic Acids Research.
05-10-2023 Congratulations to Quanhua and Ruichao! The pan-glioma evolution paper has been published by Science Translational Medicine.
20-09-2023 Congratulations to Yiyun Chen! The TAMo study has been selected as the cover story in VOLUME 4, ISSUE 9 of Cell Reports Medicine.
04-09-2023 Welcome joint program students, Can NI (primary advisor: Prof. Qinglu ZENG) and Mengqi YANG (primary advisor: Prof. Kun SUN), for joining us.