Welcome to Jiguang Wang Lab!
We are a computational laboratory in the Division of Life Science and Department of Chemical and Biological Engineering at Hong Kong University of Science and Technology (HKUST).
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression
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Tracing early predictors of glioma evolution with CELLO2
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Tumor-associated monocytes (TAMo) express EGFR ligands
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MetaNet: a machine learning method in organotropic metastases to stratify progression risk of primary tumors.
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Somatic MAP3K3 mutation Defines a Subclass of Cerebral Cavernous Malformation. Accepted for publication at American Journal of Human Genetics.
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Mutational landscape of secondary glioblastoma guides MET-targeted trial in brain tumor
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Multi-sector genomic data from 52 Glioblastoma patients reveals a multiverse model of cancer evolution.
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Longitudinal genomic data from 114 Glioblastoma patients has been used to study GBM evolution under therapy
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We have discovered a novel type of noncoding RNA, xTSS RNA, which is expressed at antisense TSS regions of genes that accumulate AID-mediated somatic mutations
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ATRAIN pipeline discovered novel long noncoding RNAs that control super-enhancer activity
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Computational method TEDG reveals order of somatic mutations in chronic lymphocytic leukemia
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A 3D computational model to simulate the multifocal glioblastoma showed the spatiotemporal model of the tumour formation.
The tumour cells were coloured by tumour lesions and mutational profiles.
Congratulations to Dr. Dong SONG. He has successfully passed the PhD exam!
Welcome Yonghong LAI to join the Wang Lab as a Research Assistant.
BAM Workshop 2024 concluded successfully. Thanks for all the speakers and participants!
Congratulations to Ran LIU who won the Hong Kong PhD Fellowship Scheme (HKPFS).
Congratulations to Haoyu WANG, who won the RedBird PhD Award for new PhD sudents.
Welcome Ran LIU and Haoyu WANG, who join the Wang Lab as RPG students.
Welcome Zhanye ZHANG to join the Wang Lab as a Research Assistant.
Congratulations to Dr. Hui WANG, who will join Harvard Medical School for postdoc study.
Congratulations to Dr. Yingxi YANG, who will join Harvard Medical School for postdoc study.
Congratulations to Yuyan who has been awarded HKUST RedBird Academic Excellence Award for Continuing PhD Students in 2023-24.
Congratulations to Zongchao who won the 3rd prize in LIFS PG Seminar! His presentation topic is Comparative genomic analysis of primary IDH1-wt glioblastoma between East Asian and ancestry of European population.
Dr. Quanhua MU will be appointed as an Assistant Professor at the Department of Applied Biology and Chemical Technology (ABCT), the Hong Kong Polytechnic University (PolyU) from July 2024. Big Congrats to Prof. MU!
Welcome Yimeng QIAO to join the lab as an RPG student!
Welcome Dr. Ming YANG to join the lab as a Postdoc Fellow!
Welcome Dr. Yanbing WANG to join the lab as a Research Assistant Professor!
Congratulations to Dong and Yiyun! The paper "Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression" has been published by Nature Genetics!
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